Permeability and ammonia selectivity in aquaporin TIP2;1: linking structure to function

Abstract Aquaporin TIP2;1 is a protein channel permeable to both water and ammonia. The structural origin of ammonia selectivity remains obscure, but experiments have revealed that a double mutation renders it impermeable to ammonia without affecting water permeability. Here, we aim to reproduce and...

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Autores principales: Viveca Lindahl, Pontus Gourdon, Magnus Andersson, Berk Hess
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/53c03b2ba91844bead5b1dffce09ba6b
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