A Metabolic Dependency for Host Isoprenoids in the Obligate Intracellular Pathogen <named-content content-type="genus-species">Rickettsia parkeri</named-content> Underlies a Sensitivity to the Statin Class of Host-Targeted Therapeutics
ABSTRACT Gram-negative bacteria in the order Rickettsiales have an obligate intracellular growth requirement, and some species cause human diseases such as typhus and spotted fever. The bacteria have evolved a dependence on essential nutrients and metabolites from the host cell as a consequence of e...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2019
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/53f1d931ef4c45f28b2d436f73249013 |
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