Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes

Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polys...

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Autores principales: Liam P. Cheeseman, Jérôme Boulanger, Lisa M. Bond, Melina Schuh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/53feebc4478245e2b737578e19101394
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