Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes

Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polys...

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Main Authors:	Liam P. Cheeseman, Jérôme Boulanger, Lisa M. Bond, Melina Schuh
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/53feebc4478245e2b737578e19101394
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spelling	oai:doaj.org-article:53feebc4478245e2b737578e191013942021-12-02T17:31:51ZTwo pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes10.1038/ncomms137262041-1723https://doaj.org/article/53feebc4478245e2b737578e191013942016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13726https://doaj.org/toc/2041-1723Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polyspermy.Liam P. CheesemanJérôme BoulangerLisa M. BondMelina SchuhNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Liam P. Cheeseman Jérôme Boulanger Lisa M. Bond Melina Schuh Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
description	Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polyspermy.
format	article
author	Liam P. Cheeseman Jérôme Boulanger Lisa M. Bond Melina Schuh
author_facet	Liam P. Cheeseman Jérôme Boulanger Lisa M. Bond Melina Schuh
author_sort	Liam P. Cheeseman
title	Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
title_short	Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
title_full	Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
title_fullStr	Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
title_full_unstemmed	Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
title_sort	two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/53feebc4478245e2b737578e19101394
work_keys_str_mv	AT liampcheeseman twopathwaysregulatecorticalgranuletranslocationtopreventpolyspermyinmouseoocytes AT jeromeboulanger twopathwaysregulatecorticalgranuletranslocationtopreventpolyspermyinmouseoocytes AT lisambond twopathwaysregulatecorticalgranuletranslocationtopreventpolyspermyinmouseoocytes AT melinaschuh twopathwaysregulatecorticalgranuletranslocationtopreventpolyspermyinmouseoocytes
_version_	1718380491553374208

Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes

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