Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polys...
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Nature Portfolio
2016
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oai:doaj.org-article:53feebc4478245e2b737578e191013942021-12-02T17:31:51ZTwo pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes10.1038/ncomms137262041-1723https://doaj.org/article/53feebc4478245e2b737578e191013942016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13726https://doaj.org/toc/2041-1723Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polyspermy.Liam P. CheesemanJérôme BoulangerLisa M. BondMelina SchuhNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q Liam P. Cheeseman Jérôme Boulanger Lisa M. Bond Melina Schuh Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes |
description |
Mammalian eggs release cortical granules to avoid being fertilized by more than a single sperm as polyspermy results in nonviable embryos. Here, the authors describe the mechanism driving translocation of the granules to the cortex in the mouse egg and show this process is essential to prevent polyspermy. |
format |
article |
author |
Liam P. Cheeseman Jérôme Boulanger Lisa M. Bond Melina Schuh |
author_facet |
Liam P. Cheeseman Jérôme Boulanger Lisa M. Bond Melina Schuh |
author_sort |
Liam P. Cheeseman |
title |
Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes |
title_short |
Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes |
title_full |
Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes |
title_fullStr |
Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes |
title_full_unstemmed |
Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes |
title_sort |
two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/53feebc4478245e2b737578e19101394 |
work_keys_str_mv |
AT liampcheeseman twopathwaysregulatecorticalgranuletranslocationtopreventpolyspermyinmouseoocytes AT jeromeboulanger twopathwaysregulatecorticalgranuletranslocationtopreventpolyspermyinmouseoocytes AT lisambond twopathwaysregulatecorticalgranuletranslocationtopreventpolyspermyinmouseoocytes AT melinaschuh twopathwaysregulatecorticalgranuletranslocationtopreventpolyspermyinmouseoocytes |
_version_ |
1718380491553374208 |