TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres.

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Autores principales: Juan J. Montero, Isabel López-Silanes, Diego Megías, Mario F. Fraga, Álvaro Castells-García, Maria A. Blasco
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/541294edad334aa0b53e65fbfb2bc59b
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