TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres.
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Nature Portfolio
2018
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oai:doaj.org-article:541294edad334aa0b53e65fbfb2bc59b2021-12-02T15:34:18ZTERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin10.1038/s41467-018-03916-32041-1723https://doaj.org/article/541294edad334aa0b53e65fbfb2bc59b2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03916-3https://doaj.org/toc/2041-1723Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres.Juan J. MonteroIsabel López-SilanesDiego MegíasMario F. FragaÁlvaro Castells-GarcíaMaria A. BlascoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q |
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Science Q Juan J. Montero Isabel López-Silanes Diego Megías Mario F. Fraga Álvaro Castells-García Maria A. Blasco TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin |
description |
Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres. |
format |
article |
author |
Juan J. Montero Isabel López-Silanes Diego Megías Mario F. Fraga Álvaro Castells-García Maria A. Blasco |
author_facet |
Juan J. Montero Isabel López-Silanes Diego Megías Mario F. Fraga Álvaro Castells-García Maria A. Blasco |
author_sort |
Juan J. Montero |
title |
TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin |
title_short |
TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin |
title_full |
TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin |
title_fullStr |
TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin |
title_full_unstemmed |
TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin |
title_sort |
terra recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/541294edad334aa0b53e65fbfb2bc59b |
work_keys_str_mv |
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1718386899203129344 |