TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres.

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Autores principales: Juan J. Montero, Isabel López-Silanes, Diego Megías, Mario F. Fraga, Álvaro Castells-García, Maria A. Blasco
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Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/541294edad334aa0b53e65fbfb2bc59b
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spelling oai:doaj.org-article:541294edad334aa0b53e65fbfb2bc59b2021-12-02T15:34:18ZTERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin10.1038/s41467-018-03916-32041-1723https://doaj.org/article/541294edad334aa0b53e65fbfb2bc59b2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03916-3https://doaj.org/toc/2041-1723Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres.Juan J. MonteroIsabel López-SilanesDiego MegíasMario F. FragaÁlvaro Castells-GarcíaMaria A. BlascoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Juan J. Montero
Isabel López-Silanes
Diego Megías
Mario F. Fraga
Álvaro Castells-García
Maria A. Blasco
TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
description Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres.
format article
author Juan J. Montero
Isabel López-Silanes
Diego Megías
Mario F. Fraga
Álvaro Castells-García
Maria A. Blasco
author_facet Juan J. Montero
Isabel López-Silanes
Diego Megías
Mario F. Fraga
Álvaro Castells-García
Maria A. Blasco
author_sort Juan J. Montero
title TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
title_short TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
title_full TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
title_fullStr TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
title_full_unstemmed TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
title_sort terra recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/541294edad334aa0b53e65fbfb2bc59b
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