TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres.

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Autores principales: Juan J. Montero, Isabel López-Silanes, Diego Megías, Mario F. Fraga, Álvaro Castells-García, Maria A. Blasco
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
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Acceso en línea:https://doaj.org/article/541294edad334aa0b53e65fbfb2bc59b
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