TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
Long non-coding RNA TERRAs are essential for telomere protection and telomere length maintenance. Here the authors report a role for TERRAs in telomeric heterochromatin formation by recruiting Polycomb Repressive Complex 2 to telomeres.
Enregistré dans:
Auteurs principaux: | Juan J. Montero, Isabel López-Silanes, Diego Megías, Mario F. Fraga, Álvaro Castells-García, Maria A. Blasco |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/541294edad334aa0b53e65fbfb2bc59b |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Telomeric RNAs are essential to maintain telomeres
par: Juan José Montero, et autres
Publié: (2016) -
Telomere lengths correlate with fitness but assortative mating by telomeres confers no benefit to fledgling recruitment
par: Rebecca C. Young, et autres
Publié: (2021) -
CTCF driven TERRA transcription facilitates completion of telomere DNA replication
par: Kate Beishline, et autres
Publié: (2017) -
Association between genetic variants in DNA and histone methylation and telomere length.
par: Sangmi Kim, et autres
Publié: (2012) -
Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila
par: Ryan Yee Wei Teo, et autres
Publié: (2018)