Assessment of gentamicin and cisplatin-induced kidney damage mediated via necrotic and apoptosis genes in albino rats

Assessment of gentamicin and cisplatin-induced kidney damage mediated via necrotic and apoptosis genes in albino rats

Abstract Background Gentamicin (GM) is a low-cost, low-resistance antibiotic commonly used to treat gram-negative bacterial diseases. Cisplatin (Csp) is a platinum-derived anti-neoplastic agent. This experiment aimed to identify the early signs of gentamicin and cisplatin-induced nephrotoxicity in r...

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Bibliographic Details
Main Authors: Tarek Kamal Abouzed, Eman Abd Elrahman Sherif, Mohamed El Sayed Barakat, Kadry Mohamed Sadek, Adil Aldhahrani, Nasr Elsayed Nasr, Ehab Eldomany, Khaled Khailo, Doaa Abdallha Dorghamm
Format: article
Language:EN
Published: BMC 2021
Subjects:
Gentamycin
Cisplatin
Nephrotoxicity
TNFα
Caspase 3
Bax
Veterinary medicine
SF600-1100
Online Access:https://doaj.org/article/5423bcf856564e5485f8ae58f05c5092
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https://doaj.org/article/5423bcf856564e5485f8ae58f05c5092

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