Single-Cell Analysis of the Plasmablast Response to <named-content content-type="genus-species">Vibrio cholerae</named-content> Demonstrates Expansion of Cross-Reactive Memory B Cells
ABSTRACT We characterized the acute B cell response in adults with cholera by analyzing the repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) generated from single-cell-sorted plasmablasts. We found that the cholera-induced responses were characterized by hi...
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2016
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| Accès en ligne: | https://doaj.org/article/545c93248a4d4ab2b5a66d76c072274b |
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