Single-Cell Analysis of the Plasmablast Response to <named-content content-type="genus-species">Vibrio cholerae</named-content> Demonstrates Expansion of Cross-Reactive Memory B Cells

Single-Cell Analysis of the Plasmablast Response to <named-content content-type="genus-species">Vibrio cholerae</named-content> Demonstrates Expansion of Cross-Reactive Memory B Cells

ABSTRACT We characterized the acute B cell response in adults with cholera by analyzing the repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) generated from single-cell-sorted plasmablasts. We found that the cholera-induced responses were characterized by hi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Robert C. Kauffman, Taufiqur R. Bhuiyan, Rie Nakajima, Leslie M. Mayo-Smith, Rasheduzzaman Rashu, Mohammad Rubel Hoq, Fahima Chowdhury, Ashraful Islam Khan, Atiqur Rahman, Siddhartha K. Bhaumik, Levelle Harris, Justin T. O'Neal, Jessica F. Trost, Nur Haq Alam, Algis Jasinskas, Emmanuel Dotsey, Meagan Kelly, Richelle C. Charles, Peng Xu, Pavol Kováč, Stephen B. Calderwood, Edward T. Ryan, Phillip L. Felgner, Firdausi Qadri, Jens Wrammert, Jason B. Harris
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/545c93248a4d4ab2b5a66d76c072274b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares