Host-Directed Antimicrobial Drugs with Broad-Spectrum Efficacy against Intracellular Bacterial Pathogens

ABSTRACT We sought a new approach to treating infections by intracellular bacteria, namely, by altering host cell functions that support their growth. We screened a library of 640 Food and Drug Administration (FDA)-approved compounds for agents that render THP-1 cells resistant to infection by four...

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Autores principales: Daniel M. Czyż, Lakshmi-Prasad Potluri, Neeta Jain-Gupta, Sean P. Riley, Juan J. Martinez, Theodore L. Steck, Sean Crosson, Howard A. Shuman, Joëlle E. Gabay
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/54603682a15940f6ad10ceded787511a
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