Host-Directed Antimicrobial Drugs with Broad-Spectrum Efficacy against Intracellular Bacterial Pathogens
ABSTRACT We sought a new approach to treating infections by intracellular bacteria, namely, by altering host cell functions that support their growth. We screened a library of 640 Food and Drug Administration (FDA)-approved compounds for agents that render THP-1 cells resistant to infection by four...
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Autores principales: | Daniel M. Czyż, Lakshmi-Prasad Potluri, Neeta Jain-Gupta, Sean P. Riley, Juan J. Martinez, Theodore L. Steck, Sean Crosson, Howard A. Shuman, Joëlle E. Gabay |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/54603682a15940f6ad10ceded787511a |
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