Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aβ fibrils
Abstract Alzheimer’s disease is characterized by neuritic plaques, the main protein components of which are β-amyloid (Aβ) peptides deposited as β-sheet-rich amyloid fibrils. Cerebral Amyloid Angiopathy (CAA) consists of cerebrovascular deposits of Aβ peptides; it usually accompanies Alzheimer’s dis...
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Autores principales: | Kathryn P. Scherpelz, Songlin Wang, Peter Pytel, Rama S. Madhurapantula, Atul K. Srivastava, Joseph R. Sachleben, Joseph Orgel, Yoshitaka Ishii, Stephen C. Meredith |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/549a89f7338448fd9a222cd6a6278088 |
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