Inhibition of TRPV1 channels by a naturally occurring omega-9 fatty acid reduces pain and itch

TRPV1 channels are known to mediate pathological pain and itch. Here, the authors find a naturally occurring fatty acid, oleic acid, acts as a TRPV1 antagonist and can modulate capsaicin and histamine-mediated pain and itch response in mouse models.

Guardado en:
Detalles Bibliográficos
Autores principales: Sara L. Morales-Lázaro, Itzel Llorente, Félix Sierra-Ramírez, Ana E. López-Romero, Miguel Ortíz-Rentería, Barbara Serrano-Flores, Sidney A. Simon, León D. Islas, Tamara Rosenbaum
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/54aa5cbb43274e3e806447b790722427
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!