Population Pharmacokinetics of Polymyxin B in Obese Patients for Resistant Gram-Negative Infections

Polymyxin B is an effective but potentially nephrotoxic antibiotic that is commonly used to treat resistant Gram-negative infections. As a weight-based dosing drug, obese patients may be at a high risk of nephrotoxicity. However, the pharmacokinetics and dosing recommendations for this population ar...

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Autores principales: Peile Wang, Qiwen Zhang, Min Feng, Tongwen Sun, Jing Yang, Xiaojian Zhang
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/54b12a7c1f4344fabe5c1431ad764201
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