Impaired cellular responses to cytosolic DNA or infection with Listeria monocytogenes and vaccinia virus in the absence of the murine LGP2 protein.
Innate immune signaling is crucial for detection of and the initial response to microbial pathogens. Evidence is provided indicating that LGP2, a DEXH box domain protein related to the RNA recognition receptors RIG-I and MDA5, participates in the cellular response to cytosolic double-stranded DNA (d...
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| Main Authors: | , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2011
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| Subjects: | |
| Online Access: | https://doaj.org/article/54c15943f9a84e59b0e60fe4924f325c |
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