An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

Successful anticancer immunotherapy should induce robust systemic immunity against metastases. Here, the authors engineer an inhalable nano-STING agonist, which synergizes with fractionated radiation to control lung metastases and confers long-term systemic antitumor immunity in mice.

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Auteurs principaux: Yang Liu, William N. Crowe, Lulu Wang, Yong Lu, W. Jeffrey Petty, Amyn A. Habib, Dawen Zhao
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/54ebf73015d9478d882dbc5a6522a5e5
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