Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress

Abstract Macrophages are involved in the pathophysiology of many diseases as critical cells of the innate immune system. Pyroptosis is a form of macrophage death that induces cytokinesis of phagocytic substances in the macrophages, thereby defending against infection. Dimethyl itaconate (DI) is an a...

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Autores principales: Shan-Shan Huang, Dong-Yang Guo, Bing-Bing Jia, Guo-Long Cai, Jing Yan, Yan Lu, Zhou-Xin Yang
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/54f19b449c5f41079bb108ea1fe913b2
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