Mechanistic principles of an ultra-long bovine CDR reveal strategies for antibody design
Certain bovine antibodies have ultra-long long complementarity-determining regions (CDRs) that contain a knob for antigen interaction, which is connected to the antibody through a stalk. Here, the authors combine biophysical experiments and MD simulations and show that the stalk length is critical f...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/551d369430b84beb8602ae26a8e6b65f |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!