A nanofluidic knot factory based on compression of single DNA in nanochannels

Polymer knots are important for a range of biological systems and engineering applications, yet the variables influencing knotting probability are not well understood. Here the authors develop a nanofluidic device that can detect knots and provide a free energy formalism that can quantify knotting p...

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Autores principales: Susan Amin, Ahmed Khorshid, Lili Zeng, Philip Zimny, Walter Reisner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/552bcbf1667d4397b0fb09d55e482b45
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