A nanofluidic knot factory based on compression of single DNA in nanochannels

Polymer knots are important for a range of biological systems and engineering applications, yet the variables influencing knotting probability are not well understood. Here the authors develop a nanofluidic device that can detect knots and provide a free energy formalism that can quantify knotting p...

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Bibliographic Details
Main Authors: Susan Amin, Ahmed Khorshid, Lili Zeng, Philip Zimny, Walter Reisner
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
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Online Access:https://doaj.org/article/552bcbf1667d4397b0fb09d55e482b45
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