Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals

Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals

Abstract Background Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X chromosome is inactive. Moreover, the inactive...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Irene Talon, Adrian Janiszewski, Bart Theeuwes, Thomas Lefevre, Juan Song, Greet Bervoets, Lotte Vanheer, Natalie De Geest, Suresh Poovathingal, Ryan Allsop, Jean-Christophe Marine, Florian Rambow, Thierry Voet, Vincent Pasque
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
X chromosome upregulation
X chromosome reactivation
Chromatin accessibility
Gene regulatory networks
iPSC reprogramming
Gene dosage compensation
Biology (General)
QH301-705.5
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/553698c5364b4b4abcd02d2908aac7a2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/553698c5364b4b4abcd02d2908aac7a2

Ejemplares similares