Developmental exposure of mice to dioxin promotes transgenerational testicular inflammation and an increased risk of preterm birth in unexposed mating partners.

TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin, commonly known as dioxin) is a ubiquitous environmental contaminant and known endocrine disruptor. Using a mouse model, we previously found that adult female mice exposed in utero to TCDD (F1 generation) as well as multiple subsequent generations (F2-F4) ex...

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Auteurs principaux: Kaylon L Bruner-Tran, Tianbing Ding, Kallie B Yeoman, Anthony Archibong, Joe A Arosh, Kevin G Osteen
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/55511374c7a244a68506538589080e25
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