Evolutionary history expands the range of signaling interactions in hybrid multikinase networks

Evolutionary history expands the range of signaling interactions in hybrid multikinase networks

Abstract Two-component systems (TCSs) are ubiquitous signaling pathways, typically comprising a sensory histidine kinase (HK) and a response regulator, which communicate via intermolecular kinase-to-receiver domain phosphotransfer. Hybrid HKs constitute non-canonical TCS signaling pathways, with tra...

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Bibliographic Details
Main Authors: Philippe Ortet, Sylvain Fochesato, Anne-Florence Bitbol, David E. Whitworth, David Lalaouna, Catherine Santaella, Thierry Heulin, Wafa Achouak, Mohamed Barakat
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/555b259ad1ec4d8982e71b4c4ea18d7f
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