The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survival

Precision medicine needs prognostic markers to select the patients that will benefit more from targeted therapy. Authors show here that high level of baseline T cell receptor diversity is an indicator of favourable prognosis in multiple cancer types, and monoclonal expansion of T-cells correlates wi...

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Autores principales: Sara Valpione, Piyushkumar A. Mundra, Elena Galvani, Luca G. Campana, Paul Lorigan, Francesco De Rosa, Avinash Gupta, John Weightman, Sarah Mills, Nathalie Dhomen, Richard Marais
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5580ae6b92b14a67a7ff151b6081830b
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