Sequence features of retrotransposons allow for epigenetic variability

Transposable elements (TEs) are mobile genetic elements that make up a large fraction of mammalian genomes. While select TEs have been co-opted in host genomes to have function, the majority of these elements are epigenetically silenced by DNA methylation in somatic cells. However, some TEs in mice,...

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Bibliographic Details
Main Authors: Kevin R Costello, Amy Leung, Candi Trac, Michael Lee, Mudaser Basam, J Andrew Pospisilik, Dustin E Schones
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
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Online Access:https://doaj.org/article/55ac6a019e3446ad92dcb3e7b15bda15
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