CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves

NAD+ and cognitive hypersensitivity during aging Cognitive dysfunction is one of the most concerning outcomes in global population aging. However, the mechanisms of cognitive impairment during aging remain elusive. We found that in old mice, levels of nicotinamide adenine dinucleotide (NAD+), an ess...

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Auteurs principaux: Sean Johnson, David F. Wozniak, S. Imai
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/5620c8e0b04c4040b4846d81718e1b72
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