Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin

Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin

Abstract Alzheimer’s disease (AD) is a very frequent neurodegenerative disorder characterized by an accumulation of amyloid-β (Aβ). Acitretin, a retinoid-derivative and approved treatment for Psoriasis vulgaris, increases non-amyloidogenic Amyloid-Precursor-Protein-(APP)-processing, prevents Aβ-prod...

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Main Authors: Anna A. Lauer, Daniel Janitschke, Malena dos Santos Guilherme, Vu Thu Thuy Nguyen, Cornel M. Bachmann, Sen Qiao, Bianca Schrul, Ulrich Boehm, Heike S. Grimm, Tobias Hartmann, Kristina Endres, Marcus O. W. Grimm
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/5639c0b6d26b424195703800c12d0d3c
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https://doaj.org/article/5639c0b6d26b424195703800c12d0d3c

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