Reduced lifespan of erythrocytes in Dahl/Salt sensitive rats is the cause of the renal proximal tubule damage

Reduced lifespan of erythrocytes in Dahl/Salt sensitive rats is the cause of the renal proximal tubule damage

Abstract We studied the mechanisms of anemia and the influence of anemia on renal pathology in Dahl/Salt Sensitive (Dahl/SS) rat, a model of cardio-renal-anemia syndrome. Erythrocyte lifespan was shortened and associated with decreased hemoglobin level in the Dahl/SS rats given high-salt diet. Serum...

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Main Authors: Eri Manabe, Satoyasu Ito, Yoshiya Ohno, Toshiyuki Tanaka, Yoshiro Naito, Naoko Sasaki, Masanori Asakura, Tohru Masuyama, Masaharu Ishihara, Takeshi Tsujino
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/56700e5c20e7418aac974b3ec81a2151
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