Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery

Current genome mining methods predict many putative non-ribosomal peptides (NRPs) from their corresponding biosynthetic gene clusters, but it remains unclear which of those exist in nature and how to identify their post-assembly modifications. Here, the authors develop NRPminer, a modification-toler...

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Bibliographic Details
Main Authors: Bahar Behsaz, Edna Bode, Alexey Gurevich, Yan-Ni Shi, Florian Grundmann, Deepa Acharya, Andrés Mauricio Caraballo-Rodríguez, Amina Bouslimani, Morgan Panitchpakdi, Annabell Linck, Changhui Guan, Julia Oh, Pieter C. Dorrestein, Helge B. Bode, Pavel A. Pevzner, Hosein Mohimani
Format: article
Language:EN
Published: Nature Portfolio 2021
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Q
Online Access:https://doaj.org/article/56701c0cd5c2408cb5012222fe11866d
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