Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1.
Coronaviruses are a family of large positive-sense RNA viruses that are responsible for a wide range of important veterinary and human diseases. Nsp1 has been shown to have an important role in the pathogenetic mechanisms of coronaviruses in vivo. To assess the function of a relatively conserved dom...
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Auteurs principaux: | , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/568bccf523a4441ba46f88fde068a538 |
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