Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1.

Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1.

Coronaviruses are a family of large positive-sense RNA viruses that are responsible for a wide range of important veterinary and human diseases. Nsp1 has been shown to have an important role in the pathogenetic mechanisms of coronaviruses in vivo. To assess the function of a relatively conserved dom...

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Autores principales: Lin Lei, Sun Ying, Luo Baojun, Yang Yi, He Xiang, Su Wenli, Sun Zounan, Guo Deyin, Zhu Qingyu, Liu Jingmei, Chang Guohui
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/568bccf523a4441ba46f88fde068a538
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