A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies

Faster, higher throughput antibody engineering methods are needed. Here the authors present CeVICA, a cell-free nanobody engineering platform using ribosome display and computational clustering analysis for in vitro selection; they use this to develop nanobodies against the RBD of SARS-CoV-2 spike p...

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Auteurs principaux: Xun Chen, Matteo Gentili, Nir Hacohen, Aviv Regev
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/56b2b7942e424f41b5a4614d612ffcf2
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