HIV-1 Vpr Reprograms CLR4<sup>DCAF1</sup> E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 Infection

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HIV-1 Vpr Reprograms CLR4<sup>DCAF1</sup> E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 Infection

ABSTRACT Viral accessory proteins hijack host cell E3 ubiquitin ligases to antagonize innate/intrinsic defenses and thereby provide a more permissive environment for virus replication. Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr reprograms CRL4DCAF1 E3 to antagonize select post...

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Autores principales:	Junpeng Yan, Ming-Chieh Shun, Caili Hao, Yi Zhang, Juan Qian, Kasia Hrecka, Maria DeLucia, Christina Monnie, Jinwoo Ahn, Jacek Skowronski
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2018
Materias:	DNA repair human immunodeficiency virus innate immunity protein degradation ubiquitination Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/56ce2447f8324b7eadd44ac5a495e2e4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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