Optimization of anti-ADAMTS13 antibodies for the treatment of ADAMTS13-related bleeding disorder in patients receiving circulatory assist device support

Abstract ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type-1 motif 13)-related bleeding disorder has been frequently observed as a life-threatening clinical complication in patients carrying a circulatory assist device. Currently, treatment modalities for the bleeding disor...

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Autores principales: Toshihiro Ito, Takeharu Minamitani, Masaki Hayakawa, Ryota Otsubo, Hiroki Akiba, Kouhei Tsumoto, Masanori Matsumoto, Teruhito Yasui
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/56ea2f8987bd4ff3a9909e359a9b94c8
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