Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner.

Opiates are among the most prescribed drugs for pain management. However, morphine use or abuse results in significant gut bacterial translocation and predisposes patients to serious infections with gut origin. The mechanism underlying this defect is still unknown. In this report, we investigated th...

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Autores principales: Jingjing Meng, Haidong Yu, Jing Ma, Jinghua Wang, Santanu Banerjee, Rick Charboneau, Roderick A Barke, Sabita Roy
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/56f75733eb584cd790e2410f436f5063
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