Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients

Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients

ABSTRACT Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common prion disease in humans and has been iatrogenically transmitted through corneal graft transplantation. Approximately 40% of sCJD patients develop visual or oculomotor symptoms and may seek ophthalmological consultation. Here we us...

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Auteurs principaux: Christina D. Orrù, Katrin Soldau, Christian Cordano, Jorge Llibre-Guerra, Ari J. Green, Henry Sanchez, Bradley R. Groveman, Steven D. Edland, Jiri G. Safar, Jonathan H. Lin, Byron Caughey, Michael D. Geschwind, Christina J. Sigurdson
Format: article
Langue:EN
Publié: American Society for Microbiology 2018
Sujets:
Creutzfeldt-Jakob disease
RT-QuIC
eye
prion
Microbiology
QR1-502
Accès en ligne:https://doaj.org/article/5703229a19df4bc7bb1051cfb6550757
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https://doaj.org/article/5703229a19df4bc7bb1051cfb6550757

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