A novel biosafety level 2 compliant tuberculosis infection model using a ΔleuDΔpanCD double auxotroph of Mycobacterium tuberculosis H37Rv and Galleria mellonella

Mammalian infection models have contributed significantly to our understanding of the host-mycobacterial interaction, revealing potential mechanisms and targets for novel antimycobacterial therapeutics. However, the use of conventional mammalian models such as mice, are typically expensive, high mai...

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Autores principales: Masanori Asai, Yanwen Li, John Spiropoulos, William Cooley, David Everest, Brian D. Robertson, Paul R. Langford, Sandra M. Newton
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2020
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Acceso en línea:https://doaj.org/article/572ae8bfa51e40ebb1855c127c6572d0
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