The anti-inflammatory agent bindarit acts as a modulator of fatty acid-binding protein 4 in human monocytic cells

Abstract We investigated the cellular and molecular mechanisms by which bindarit, a small indazolic derivative with prominent anti-inflammatory effects, exerts its immunoregulatory activity in lipopolysaccharide (LPS) stimulated human monocytic cells. We found that bindarit differentially regulates...

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Autores principales: Sergio Oddi, Lucia Scipioni, Antonio Totaro, Clotilde Angelucci, Beatrice Dufrusine, Annalaura Sabatucci, Daniel Tortolani, Isabella Coletta, Maria Alessandra Alisi, Lorenzo Polenzani, Michael Assfalg, Carlo Caltagirone, Enrico Dainese, Mauro Maccarrone
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/572eb2b99d5749e3b72bf31cc3872ede
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