Inhibition of ADAM10 ameliorates doxorubicin-induced cardiac remodeling by suppressing N-cadherin cleavage

The present research was designed to examine the effects of disintegrin metalloproteinases 10 (ADAM10) on the doxorubicin (DOX)-induced dilated cardiomyopathy (DCM) and the mechanisms involved, with a focus on ADAM10-dependent cleavage of N-cadherin. The present study constructed recombinant lentivi...

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Autores principales: Li Xiaoou, Pan Feng, He Bing, Fang Chengzhi
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
Materias:
dcm
Acceso en línea:https://doaj.org/article/5744b737e63c4fcfb88d573a8ea310f3
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