Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin

The functional role of dissociation of long ncRNAs from chromatin is poorly understood. Here, the authors provide evidence that release of the long ncRNA AROD from chromatin enhances DKK1 transcription, and suggest that this regulatory mechanism of transcription applies to a subset of long ncRNAs.

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Autores principales: Evgenia Ntini, Annita Louloupi, Julia Liz, Jose M. Muino, Annalisa Marsico, Ulf Andersson Vang Ørom
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/577c083a37dd46d1bd8361053bbf1dba
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