Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin

The functional role of dissociation of long ncRNAs from chromatin is poorly understood. Here, the authors provide evidence that release of the long ncRNA AROD from chromatin enhances DKK1 transcription, and suggest that this regulatory mechanism of transcription applies to a subset of long ncRNAs.

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Autores principales:	Evgenia Ntini, Annita Louloupi, Julia Liz, Jose M. Muino, Annalisa Marsico, Ulf Andersson Vang Ørom
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/577c083a37dd46d1bd8361053bbf1dba
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spelling	oai:doaj.org-article:577c083a37dd46d1bd8361053bbf1dba2021-12-02T14:38:53ZLong ncRNA A-ROD activates its target gene DKK1 at its release from chromatin10.1038/s41467-018-04100-32041-1723https://doaj.org/article/577c083a37dd46d1bd8361053bbf1dba2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04100-3https://doaj.org/toc/2041-1723The functional role of dissociation of long ncRNAs from chromatin is poorly understood. Here, the authors provide evidence that release of the long ncRNA AROD from chromatin enhances DKK1 transcription, and suggest that this regulatory mechanism of transcription applies to a subset of long ncRNAs.Evgenia NtiniAnnita LouloupiJulia LizJose M. MuinoAnnalisa MarsicoUlf Andersson Vang ØromNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Evgenia Ntini Annita Louloupi Julia Liz Jose M. Muino Annalisa Marsico Ulf Andersson Vang Ørom Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
description	The functional role of dissociation of long ncRNAs from chromatin is poorly understood. Here, the authors provide evidence that release of the long ncRNA AROD from chromatin enhances DKK1 transcription, and suggest that this regulatory mechanism of transcription applies to a subset of long ncRNAs.
format	article
author	Evgenia Ntini Annita Louloupi Julia Liz Jose M. Muino Annalisa Marsico Ulf Andersson Vang Ørom
author_facet	Evgenia Ntini Annita Louloupi Julia Liz Jose M. Muino Annalisa Marsico Ulf Andersson Vang Ørom
author_sort	Evgenia Ntini
title	Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
title_short	Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
title_full	Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
title_fullStr	Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
title_full_unstemmed	Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
title_sort	long ncrna a-rod activates its target gene dkk1 at its release from chromatin
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/577c083a37dd46d1bd8361053bbf1dba
work_keys_str_mv	AT evgeniantini longncrnaarodactivatesitstargetgenedkk1atitsreleasefromchromatin AT annitalouloupi longncrnaarodactivatesitstargetgenedkk1atitsreleasefromchromatin AT julializ longncrnaarodactivatesitstargetgenedkk1atitsreleasefromchromatin AT josemmuino longncrnaarodactivatesitstargetgenedkk1atitsreleasefromchromatin AT annalisamarsico longncrnaarodactivatesitstargetgenedkk1atitsreleasefromchromatin AT ulfanderssonvangørom longncrnaarodactivatesitstargetgenedkk1atitsreleasefromchromatin
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Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin

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