Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription

Recent investigations suggest that G-protein-coupled receptors (GPCRs) can signal during intracellular trafficking. Here the authors use fluorescence microscopy approaches to directly visualize and investigate functional consequences of GPCR-mediated signaling at the Golgi/trans-Golgi network.

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Autores principales: Amod Godbole, Sandra Lyga, Martin J. Lohse, Davide Calebiro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/579404a03c0147afacf9210a0eb19e7e
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