Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription

Recent investigations suggest that G-protein-coupled receptors (GPCRs) can signal during intracellular trafficking. Here the authors use fluorescence microscopy approaches to directly visualize and investigate functional consequences of GPCR-mediated signaling at the Golgi/trans-Golgi network.

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Autores principales:	Amod Godbole, Sandra Lyga, Martin J. Lohse, Davide Calebiro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/579404a03c0147afacf9210a0eb19e7e
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spelling	oai:doaj.org-article:579404a03c0147afacf9210a0eb19e7e2021-12-02T17:06:06ZInternalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription10.1038/s41467-017-00357-22041-1723https://doaj.org/article/579404a03c0147afacf9210a0eb19e7e2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00357-2https://doaj.org/toc/2041-1723Recent investigations suggest that G-protein-coupled receptors (GPCRs) can signal during intracellular trafficking. Here the authors use fluorescence microscopy approaches to directly visualize and investigate functional consequences of GPCR-mediated signaling at the Golgi/trans-Golgi network.Amod GodboleSandra LygaMartin J. LohseDavide CalebiroNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amod Godbole Sandra Lyga Martin J. Lohse Davide Calebiro Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription
description	Recent investigations suggest that G-protein-coupled receptors (GPCRs) can signal during intracellular trafficking. Here the authors use fluorescence microscopy approaches to directly visualize and investigate functional consequences of GPCR-mediated signaling at the Golgi/trans-Golgi network.
format	article
author	Amod Godbole Sandra Lyga Martin J. Lohse Davide Calebiro
author_facet	Amod Godbole Sandra Lyga Martin J. Lohse Davide Calebiro
author_sort	Amod Godbole
title	Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription
title_short	Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription
title_full	Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription
title_fullStr	Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription
title_full_unstemmed	Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription
title_sort	internalized tsh receptors en route to the tgn induce local gs-protein signaling and gene transcription
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/579404a03c0147afacf9210a0eb19e7e
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Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription

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