Ribosomal Elongation Factor 4 Promotes Cell Death Associated with Lethal Stress

ABSTRACT Ribosomal elongation factor 4 (EF4) is highly conserved among bacteria, mitochondria, and chloroplasts. However, the EF4-encoding gene, lepA, is nonessential and its deficiency shows no growth or fitness defect. In purified systems, EF4 back-translocates stalled, posttranslational ribosomes...

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Auteurs principaux: Liping Li, Yuzhi Hong, Gan Luan, Michael Mosel, Muhammad Malik, Karl Drlica, Xilin Zhao
Format: article
Langue:EN
Publié: American Society for Microbiology 2014
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Accès en ligne:https://doaj.org/article/57a842d42f714ce1b1a09aafe4542e8b
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