Highly efficient expression of interleukin-2 under the control of rabbit β-globin intron II gene enhances protective immune responses of porcine reproductive and respiratory syndrome (PRRS) DNA vaccine in pigs.

Highly efficient expression of interleukin-2 under the control of rabbit β-globin intron II gene enhances protective immune responses of porcine reproductive and respiratory syndrome (PRRS) DNA vaccine in pigs.

Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) had caused catastrophic losses in swine industry in China. The current inactivated vaccine provided only limited protection, and the attenuated live vaccine could protect piglets against the HP-PRRSV but there was a pos...

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Autores principales: Yijun Du, Yu Lu, Xinglong Wang, Jing Qi, Jiyu Liu, Yue Hu, Feng Li, Jiaqiang Wu, Lihui Guo, Junzhen Liu, Haiying Tao, Wenbo Sun, Lei Chen, Xiaoyan Cong, Sufang Ren, Jianli Shi, Jun Li, Jinbao Wang, Baohua Huang, Renzhong Wan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/57c5125fa0da49088be267d0f29b9e74
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https://doaj.org/article/57c5125fa0da49088be267d0f29b9e74

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