Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells.

Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells.

<h4>Background</h4>Using human brain microvascular endothelial cells (HBMECs) as an in vitro model for how African trypanosomes cross the human blood-brain barrier (BBB) we recently reported that the parasites cross the BBB by generating calcium activation signals in HBMECs through the a...

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Bibliographic Details
Main Authors: Dennis J Grab, Jose C Garcia-Garcia, Olga V Nikolskaia, Yuri V Kim, Amanda Brown, Carlos A Pardo, Yongqing Zhang, Kevin G Becker, Brenda A Wilson, Ana Paula C de A Lima, Julio Scharfstein, J Stephen Dumler
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Online Access:https://doaj.org/article/57eeeeb3c8e24f6f84c9d7feca2de86e
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https://doaj.org/article/57eeeeb3c8e24f6f84c9d7feca2de86e

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