Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells.

<h4>Background</h4>Using human brain microvascular endothelial cells (HBMECs) as an in vitro model for how African trypanosomes cross the human blood-brain barrier (BBB) we recently reported that the parasites cross the BBB by generating calcium activation signals in HBMECs through the a...

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Auteurs principaux: Dennis J Grab, Jose C Garcia-Garcia, Olga V Nikolskaia, Yuri V Kim, Amanda Brown, Carlos A Pardo, Yongqing Zhang, Kevin G Becker, Brenda A Wilson, Ana Paula C de A Lima, Julio Scharfstein, J Stephen Dumler
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
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Accès en ligne:https://doaj.org/article/57eeeeb3c8e24f6f84c9d7feca2de86e
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