The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3.
The innate immune response constitutes the first line of host defence that limits viral spread and plays an important role in the activation of adaptive immune response. Viral components are recognized by specific host pathogen recognition receptors triggering the activation of IRF3. IRF3, along wit...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2011
|
| Subjects: | |
| Online Access: | https://doaj.org/article/58181cad50584114a4df3604a3b1c1a0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|