Wnt antagonist FRZB is a muscle biomarker of denervation atrophy in amyotrophic lateral sclerosis
Abstract Skeletal muscle and the neuromuscular junction are the earliest sites to manifest pathological changes in amyotrophic lateral sclerosis (ALS). Based on prior studies, we have identified a molecular signature in muscle that develops early in ALS and parallels disease progression. This signat...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/5818ae8790184c18a4eb0a039ecf46e0 |
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